Article
Novel non-Mendelian determinant involved in the control of translation accuracy in Saccharomyces cerevisiae.
Genetics - 1 Jan 2002
Volkov Kirill V, Aksenova Anna Yu, Soom Malle J, Osipov Kirill V, Svitin Anton V, Kurischko Cornelia, Shkundina Irina S, Ter-Avanesyan Michael D, Inge-Vechtomov Sergey G, Mironova Ludmila N
Abstract excerpt
Two cytoplasmically inherited determinants related by their manifestation to the control of translation accuracy were previously described in yeast. Cells carrying one of them, [PSI(+)], display a nonsense suppressor phenotype and contain a prion form of the Sup35 protein. Another element, [PIN(+)], determines the probability of de novo generation of [PSI(+)] and results from a prion form of several proteins,...
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