Article
A new multimarker test for family-based association studies.
Genetic epidemiology - 1 Jan 2007
Rakovski Cyril S, Xu Xin, Lazarus Ross, Blacker Deborah, Laird Nan M
Abstract excerpt
We propose a new multimarker test for family-based studies in candidate genes. We use simulations under different genetic models to assess the performance of competing testing strategies, characterized in this study as combinations of the following important factors: genes, statistical tests, tag single nucleotide polymorphisms (SNP) methods, number of tag SNPs and family designs. An ANOVA model is employed to...
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