Article
FBAT-SNP-PC: an approach for multiple markers and single trait in family-based association tests.
Human heredity - 1 Jan 2008
Rakovski Cyril S, Weiss Scott T, Laird Nan M, Lange Christoph
Abstract excerpt
OBJECTIVE: Develop a new test for family-based association studies and continuous traits that incorporates power- enhancing techniques from two existing testing strategies. METHODS: The new procedure initiates with an extraction of the relevant information from the variability of the genotypes and an assessment of the approximate individual markers effects and their directions. This information is incorporated in...
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