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Article

Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan.

American journal of human genetics - 1 Sept 2007

Ionita-Laza Iuliana, McQueen Matthew B, Laird Nan M, Lange Christoph

Abstract excerpt

For genomewide association (GWA) studies in family-based designs, we propose a novel two-stage strategy that weighs the association P values with the use of independently estimated weights. The association information contained in the family sample is partitioned into two orthogonal components--n...

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Identifiers

PMID: 17701906
DOI: 10.1086/519748
PMCID: PMC1950836

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17701906-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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