Article
Haplotypes of IL6 and IL10 and susceptibility to human T lymphotropic virus type I infection among children.
The Journal of infectious diseases - 1 Dec 2006
Brown Elizabeth E, Brown Brandon J, Yeager Meredith, Welch Robert, Cranston Beverly, Hanchard Barrie, Hisada Michie
Abstract excerpt
To characterize a host polygenic profile associated with susceptibility to human T lymphotropic virus type I (HTLV-I) infection, we examined common variants in 11 immune-related genes among Jamaican children born to HTLV-I-seropositive mothers. Compared with HTLV-I seronegatives, haplotypes of IL6 (-660G/-635C/-236G) and IL10 (-6653C/-1116G) were significantly associated with HTLV-I infection in children...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
