Article
Genomic analysis of Th1-Th2 cytokine genes in an AIDS cohort: identification of IL4 and IL10 haplotypes associated with the disease progression.
Genes and immunity - 1 Sept 2003
Vasilescu A, Heath S C, Ivanova R, Hendel H, Do H, Mazoyer A, Khadivpour E, Goutalier F X, Khalili K, Rappaport J, Lathrop G M, Matsuda F, Zagury J-F
Abstract excerpt
Polymorphisms of Th1-Th2 cytokine genes have previously been implicated in the rate of progression to AIDS in seropositive patients. To evaluate further the impact of these genes in the development of AIDS, we have performed an extensive genetic analysis of IL2, IL4, IL6, IL10, IL12p35 and p40, I...
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