Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

The role of apoptotic genetic polymorphisms in prostate cancer susceptibility in a North West Spain population.

Molecular genetics and genomics : MGG - 31 Mar 2026

López-Trigo N, Caeiro B, Pérez-Pérez J, Rodríguez-Alonso A, Aguín N, Rodríguez J A, Luis J R

Abstract excerpt

Apoptosis and tumor suppression prevent cell proliferation in response to genomic damage. Polymorphisms in genes involved in these pathways can alter their function, facilitating the onset of cancer. Detecting these polymorphisms would assess the individual risk of developing different types of cancer. Therefore, the main goal of this study is to analyze the association between a set of genetic polymorphisms...

Topics

Humans
Male
Prostatic Neoplasms
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide
Case-Control Studies
Spain
Apoptosis
Aged
Middle Aged
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Alleles

Body Mass Index

Risk Factors

Source

Identifiers

PMID: 41915239
DOI: 10.1007/s00438-026-02405-3

Genes

CASP9
MDM2
FAS
MDM4
BCL2
CASP7
CASP8
FASLG
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of apoptotic genetic polymorphisms in prostate cancer susceptibility in a North West Spain population.PMID 41915239Read ↗

Association of CASP3 genetic polymorphisms rs1049216, rs2705897 and rs4647603 with the risk of prostate cancer in Galicia (NW Spain).Semantic proximity Read ↗

Apoptosis gene polymorphisms and risk of prostate cancer: a hospital-based study of German patients treated with brachytherapy.Semantic proximity Read ↗

Polymorphisms and haplotypes in caspases 8 and 9 genes and risk for prostate cancer: a case-control study in cohort of North India.Semantic proximity Read ↗

Are cell cycle and apoptosis genes associated with prostate cancer risk in North Indian population?Semantic proximity Read ↗

Functional polymorphisms in cell death pathway genes FAS and FAS ligand and risk of prostate cancer in a Chinese population.Semantic proximity Read ↗

BCL2 genotypes and prostate cancer survival.Semantic proximity Read ↗

Association of CASP8 polymorphisms and cancer susceptibility: A meta-analysis.Semantic proximity Read ↗

Association Aamong Ppolymorphisms in the Aapoptosis-Rrelated NKX3-1, Caspase-3, Caspase-9, and BCL-2 Genes and Prostate Cancer Susceptibility From 9706 Cases and 12,567 Controls.Semantic proximity Read ↗

Association among polymorphisms in the apoptosis-related NKX3-1, caspase-3, caspase-9, and BCL-2 genes and prostate cancer susceptibility from 9,706 cases and 12,567 controlsSemantic proximity Read ↗

Survivin rs9904341 (G>C) polymorphism contributes to cancer risk: an updated meta-analysis of 26 studies.Semantic proximity Read ↗

Effects of Caspase 9 Gene Polymorphism in Patients with Prostate Cancer.Semantic proximity Read ↗

Polymorphic variants of the CASP3, CASP9, BCL-2 and NKX3-1 genes as candidate markers for prostate cancer susceptibility and poor prognosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.