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Article

Functional relationships between Rad18 and WRNIP1 in vertebrate cells.

Biological & pharmaceutical bulletin - 1 Nov 2006

Yoshimura Akari, Seki Masayuki, Hayashi Tomoko, Kusa Yumiko, Tada Shusuke, Ishii Yutaka, Enomoto Takemi

Abstract excerpt

The WRNIP1 protein interacts with WRN, the product of the causative gene for Werner syndrome. Mutation of the Saccharomyces cerevisiae gene MGS1, the yeast counterpart of WRNIP1, confers synthetic lethality with mutation of RAD18. To examine the functional relationship between WRNIP1 and Rad18 in higher eukaryotic cells, we generated WRNIP1-/-/-/RAD18-/- lines from chicken DT40 cells and compared them with single...

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Source

Identifiers

PMID: 17077513
DOI: 10.1248/bpb.29.2192

Genes

WRNIP1
RAD18
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional relationships between Rad18 and WRNIP1 in vertebrate cells.PMID 17077513Read ↗

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