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Article

RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells.

The EMBO journal - 15 Oct 2002

Yamashita Yukiko M, Okada Takashi, Matsusaka Takahiro, Sonoda Eiichiro, Zhao Guang Yu, Araki Kasumi, Tateishi Satoshi, Yamaizumi Masaru, Takeda Shunichi

Abstract excerpt

Translesion DNA synthesis (TLS) and homologous DNA recombination (HR) are two major pathways that account for survival after post-replicational DNA damage. TLS functions by filling gaps on a daughter strand that remain after DNA replication caused by damage on the mother strand, while HR can repair gaps and breaks using the intact sister chromatid as a template. The RAD18 gene, which is conserved from lower...

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Source

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Identifiers

PMID: 12374756
DOI: 10.1093/emboj/cdf534
PMCID: PMC129066

Genes

RAD18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells.PMID 12374756Read ↗

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