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Article

The Werner's Syndrome protein collaborates with REV1 to promote replication fork progression on damaged DNA.

DNA repair - 5 Oct 2010

Phillips Lara G, Sale Julian E

Abstract excerpt

DNA damage tolerance pathways facilitate the bypass of DNA lesions encountered during replication. These pathways can be mechanistically divided into recombinational damage avoidance and translesion synthesis, in which the lesion is directly bypassed by specialised DNA polymerases. We have recently shown distinct genetic dependencies for lesion bypass at and behind the replication fork in the avian cell line...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20691646
DOI: 10.1016/j.dnarep.2010.07.006
PMCID: PMC2956782

Genes

REV1
WRN
PCNA
RAD18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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