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Article

In vitro development of resistance to DX-619 and other quinolones in enterococci.

The Journal of antimicrobial chemotherapy - 1 Dec 2006

Wickman Paul A, Black Jennifer A, Smith Moland Ellen, Thomson Kenneth S, Hanson Nancy D

Abstract excerpt

OBJECTIVES: To investigate the molecular events involved in the development of quinolone resistance in enterococci. METHODS: Clinical isolates of Enterococcus faecium and Enterococcus faecalis were exposed to inhibitory and subinhibitory concentrations of DX-619, ciprofloxacin, levofloxacin, gatifloxacin and moxifloxacin. Mutational frequencies were calculated and susceptibility changes were determined. The...

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Identifiers

PMID: 17062613
DOI: 10.1093/jac/dkl421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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