Article
In vitro activity of DX-619, a novel des-fluoro(6) quinolone, against a panel of Streptococcus pneumoniae mutants with characterized resistance mechanisms.
Antimicrobial agents and chemotherapy - 1 Feb 2006
Wickman Paul A, Moland Ellen Smith, Black Jennifer A, Thomson Kenneth S
Abstract excerpt
The in vitro activities of DX-619 and four other quinolones were compared against Streptococcus pneumoniae mutants that contained a variety of alterations within the quinolone resistance-determining regions. DX-619 was the most potent quinolone and was least affected by the mutations.
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