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Article

Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1.

Cell - 20 Oct 2006

Meeusen Shelly, DeVay Rachel, Block Jennifer, Cassidy-Stone Ann, Wayson Sarah, McCaffery J Michael, Nunnari Jodi

Abstract excerpt

Mitochondrial outer- and inner-membrane fusion events are coupled in vivo but separable and mechanistically distinct in vitro, indicating that separate fusion machines exist in each membrane. Outer-membrane fusion requires trans interactions of the dynamin-related GTPase Fzo1, GTP hydrolysis, and an intact inner-membrane proton gradient. Inner-membrane fusion also requires GTP hydrolysis but distinctly requires...

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Identifiers

PMID: 17055438
DOI: 10.1016/j.cell.2006.09.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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