Article
A fuzzy mitochondrial fusion apparatus comes into focus.
Nature reviews. Molecular cell biology - 1 Jun 2003
Mozdy Amy D, Shaw Janet M
Abstract excerpt
Membrane fusion is fundamental to eukaryotic life. Unlike the predominant intracellular fusion machineries that fuse compartments bounded by a single membrane, the mitochondrial fusion machinery must sequentially fuse the outer and inner mitochondrial membranes. These coordinated fusion events rely on a transmembrane GTPase that is known as fuzzy onions or Fzo. Recent studies have revealed that Fzo has an...
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