Article
[Mitochondrial morphology and dynamics: actors, mechanisms and functions].
Medecine sciences : M/S - 1 Oct 2010
Sauvanet Cécile, Arnauné-Pelloquin Laetitia, David Claudine, Belenguer Pascale, Rojo Manuel
Abstract excerpt
Mitochondria are dynamic organelles that continuously move, fuse and divide. Their overall morphology, ranging from a filamentous network to a collection of isolated dots, is determined by fusion-fission equilibrium, which depends on the cellular and physiological context. The machineries of fusion and fission, that are conserved throughout evolution, include three large GTPases of the dynamin-superfamily:...
Topics
- Animals
- Biological Evolution
- Biomechanical Phenomena
- Cell Fusion
- Gene Deletion
- Gene Knockout Techniques
- Humans
- Kinetics
- Mitochondria
- Mutation
- Nervous System Diseases