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Article

Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane.

Molecular biology of the cell - 1 Jun 2003

Sesaki Hiromi, Southard Sheryl M, Yaffe Michael P, Jensen Robert E

Abstract excerpt

In Saccharomyces cerevisiae, mitochondrial fusion requires at least two outer membrane proteins, Fzo1p and Ugo1p. We provide direct evidence that the dynamin-related Mgm1 protein is also required for mitochondrial fusion. Like fzo1 and ugo1 mutants, cells disrupted for the MGM1 gene contain numerous mitochondrial fragments instead of the few long, tubular organelles seen in wild-type cells. Fragmentation of...

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Source

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Identifiers

PMID: 12808034
DOI: 10.1091/mbc.e02-12-0788
PMCID: PMC194884

Genes

DNM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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