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Disrupted in schizophrenia 1 genotype and positive symptoms in schizophrenia.

Biological psychiatry - 15 May 2007

DeRosse Pamela, Hodgkinson Colin A, Lencz Todd, Burdick Katherine E, Kane John M, Goldman David, Malhotra Anil K

Abstract excerpt

BACKGROUND: Converging evidence has demonstrated an association between the Disrupted in Schizophrenia 1 (DISC1) gene and schizophrenia (SZ). Within the DISC1 gene, a single nucleotide polymorphism (SNP), Ser704Cys, has been associated with the structure and function of the hippocampus. Because positive symptoms in SZ have also been associated with hippocampal structure and function, we hypothesized that...

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Source

Identifiers

PMID: 17054920
DOI: 10.1016/j.biopsych.2006.07.023

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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