Article
Association evidence of schizophrenia with distal genomic region of NOTCH4 in Taiwanese families.
Genes, brain, and behavior - 1 Aug 2007
Liu C-M, Liu Y-L, Fann C S-J, Chen W J, Yang W-C, Ouyang W-C, Chen C-Y, Jou Y-S, Hsieh M-H, Liu S-K, Hwang T-J, Faraone S V, Tsuang M T, Hwu H-G
Abstract excerpt
Evidence for association with schizophrenia has been reported for NOTCH4, although results have been inconsistent. Previous studies have focused on polymorphisms in the 5' promoter region and first exon of NOTCH4. Our aim was to test the association of the entire genomic region of NOTCH4 in 218 families with at least two siblings affected by schizophrenia in Taiwan. We genotyped seven single nucleotide...
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