Article
Genetic association between Notch4 polymorphisms and Japanese schizophrenics.
Psychiatric genetics - 1 Apr 2006
Shibata Nobuto, Ohnuma Tohru, Higashi Shinji, Higashi Maiko, Usui Chie, Ohkubo Taku, Watanabe Tomoko, Kitajima Akiyoshi, Ueki Akira, Nagao Masatsugu, Arai Heii
Abstract excerpt
The objective of this study was to investigate whether three single nucleotide polymorphisms of the Notch4 gene are associated with the onset of schizophrenia. To confirm the linkage disequilibrium among these three single nucleotide polymorphisms of the gene, the three single nucleotide polymorphisms were genotyped by a polymerase chain reaction-restriction-fragment length polymorphism method for all samples....
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