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Article

Five NOTCH4 polymorphisms show weak evidence for association with schizophrenia: evidence from meta-analyses.

Schizophrenia research - 1 Mar 2005

Glatt Stephen J, Wang Richard S, Yeh Yu-Chi, Tsuang Ming T, Faraone Stephen V

Abstract excerpt

NOTCH4 initially received consideration as a risk gene for schizophrenia based on its location within a region on chromosome 6p that had previously shown strong evidence for genetic linkage with the illness. The initial published test for allelic association found strong evidence for involvement of this gene in schizophrenia, but subsequent studies failed to confirm this finding. Presently, we have used...

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Source

Identifiers

PMID: 15653273
DOI: 10.1016/j.schres.2004.07.015

Genes

NOTCH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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Five NOTCH4 polymorphisms show weak evidence for association with schizophrenia: evidence from meta-analyses.PMID 15653273Read ↗

Is NOTCH4 associated with schizophrenia?Semantic proximity Read ↗

Family-based association study of the NOTCH4 gene in schizophrenia using Japanese and Chinese samples.Semantic proximity Read ↗

Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland.Semantic proximity Read ↗

A re-review of the association between the NOTCH4 locus and schizophrenia.Semantic proximity Read ↗

No evidence for association between NOTCH4 and schizophrenia in a large family-based and case-control association analysis.Semantic proximity Read ↗

A review and re-evaluation of an association between the NOTCH4 locus and schizophrenia.Semantic proximity Read ↗

NOTCH4 gene polymorphism and susceptibility to schizophrenia and schizoaffective disorder.Semantic proximity Read ↗

Association analysis of NOTCH 4 polymorphisms with schizophrenia among two independent family based samples.Semantic proximity Read ↗

Convergent lines of evidence support NOTCH4 as a schizophrenia risk gene.Semantic proximity Read ↗

Association of six polymorphisms of the NOTCH4 gene with schizophrenia in the Japanese population.Semantic proximity Read ↗

Genetic association between Notch4 polymorphisms and Japanese schizophrenics.Semantic proximity Read ↗

Neither single-marker nor haplotype analyses support an association between genetic variation near NOTCH4 and bipolar disorder.Semantic proximity Read ↗

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