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Article

A re-review of the association between the NOTCH4 locus and schizophrenia.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2012

Shayevitz Christina, Cohen Ori S, Faraone Stephen V, Glatt Stephen J

Abstract excerpt

NOTCH4 has long been identified as a candidate susceptibility gene for schizophrenia, but the collective body of genetic association studies of this gene has been less than conclusive. Recently a variant in NOTCH4 was implicated as one of the most reliably associated polymorphisms observed in a genome-wide association scan of the disorder, and the collective evidence for this polymorphism now surpasses criteria...

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Source

Identifiers

PMID: 22488909
DOI: 10.1002/ajmg.b.32050

Genes

NOTCH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A re-review of the association between the NOTCH4 locus and schizophrenia.PMID 22488909Read ↗

A review and re-evaluation of an association between the NOTCH4 locus and schizophrenia.Semantic proximity Read ↗

Convergent lines of evidence support NOTCH4 as a schizophrenia risk gene.Semantic proximity Read ↗

Is NOTCH4 associated with schizophrenia?Semantic proximity Read ↗

The NOTCH4 locus is associated with susceptibility to schizophrenia.Semantic proximity Read ↗

Family-based association study of the NOTCH4 gene in schizophrenia using Japanese and Chinese samples.Semantic proximity Read ↗

Five NOTCH4 polymorphisms show weak evidence for association with schizophrenia: evidence from meta-analyses.Semantic proximity Read ↗

Association of the NOTCH4 Gene Polymorphism rs204993 with Schizophrenia in the Chinese Han Population.Semantic proximity Read ↗

NOTCH4 gene polymorphism and susceptibility to schizophrenia and schizoaffective disorder.Semantic proximity Read ↗

Association evidence of schizophrenia with distal genomic region of NOTCH4 in Taiwanese families.Semantic proximity Read ↗

A family-based and case-control association study of the NOTCH4 gene and schizophrenia.Semantic proximity Read ↗

No evidence for association between NOTCH4 and schizophrenia in a large family-based and case-control association analysis.Semantic proximity Read ↗

Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland.Semantic proximity Read ↗

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