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Article

Functionality of intergenic transcription: an evolutionary comparison.

PLoS genetics - 13 Oct 2006

Khaitovich Philipp, Kelso Janet, Franz Henriette, Visagie Johann, Giger Thomas, Joerchel Sabrina, Petzold Ekkehard, Green Richard E, Lachmann Michael, Pääbo Svante

Abstract excerpt

Although a large proportion of human transcription occurs outside the boundaries of known genes, the functional significance of this transcription remains unknown. We have compared the expression patterns of known genes as well as intergenic transcripts within the ENCODE regions between humans and chimpanzees in brain, heart, testis, and lymphoblastoid cell lines. We find that intergenic transcripts show patterns...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17040132
DOI: 10.1371/journal.pgen.0020171
PMCID: PMC1599769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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