Article
Gene expression and adaptive noncoding changes during human evolution.
BMC genomics - 5 Jun 2017
Babbitt Courtney C, Haygood Ralph, Nielsen William J, Wray Gregory A
Abstract excerpt
BACKGROUND: Despite evidence for adaptive changes in both gene expression and non-protein-coding, putatively regulatory regions of the genome during human evolution, the relationship between gene expression and adaptive changes in cis-regulatory regions remains unclear. RESULTS: Here we present new measurements of gene expression in five tissues of humans and chimpanzees, and use them to assess this relationship....
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