Article
Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq.
PLoS computational biology - 1 Jul 2010
Xu Augix Guohua, He Liu, Li Zhongshan, Xu Ying, Li Mingfeng, Fu Xing, Yan Zheng, Yuan Yuan, Menzel Corinna, Li Na, Somel Mehmet, Hu Hao, Chen Wei, Pääbo Svante, Khaitovich Philipp
Abstract excerpt
Transcription is the first step connecting genetic information with an organism's phenotype. While expression of annotated genes in the human brain has been characterized extensively, our knowledge about the scope and the conservation of transcripts located outside of the known genes' boundaries is limited. Here, we use high-throughput transcriptome sequencing (RNA-Seq) to characterize the total non-ribosomal...
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