Article
Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs.
PLoS genetics - 1 Jun 2013
Hangauer Matthew J, Vaughn Ian W, McManus Michael T
Abstract excerpt
Known protein coding gene exons compose less than 3% of the human genome. The remaining 97% is largely uncharted territory, with only a small fraction characterized. The recent observation of transcription in this intergenic territory has stimulated debate about the extent of intergenic transcription and whether these intergenic RNAs are functional. Here we directly observed with a large set of RNA-seq data...
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