Article

Cross-tissue isoform switches by human transcription factors suggest a widespread regulatory mechanism

2024-11-29

Abstract excerpt

Many human genes, including transcription factor (TF) genes, produce alternative coding isoforms. Although some alternative coding TF isoforms have been experimentally studied, a genome-wide characterisation of all such isoforms in normal human physiology is still lacking. Here, we integrate RNA sequencing and protein domain data to reveal the expression levels, tissue specificity and putative functional classes o...

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Literature Corpus work: 93e9c48a-d32e-5033-ba28-d3fc8cb03e18
DOI: 10.1101/2024.11.28.625692

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