Article
Reactivity of cloned, expressed human Fc gamma RIII isoforms with monoclonal antibodies which distinguish cell-type-specific and allelic forms of Fc gamma RIII.
International immunology - 1 Jan 1990
Trounstine M L, Peltz G A, Yssel H, Huizinga T W, von dem Borne A E, Spits H, Moore K W
Abstract excerpt
We have isolated and expressed a cDNA encoding human NK cell Fc gamma RIII. The NK cell cDNA differs from the neutrophil Fc gamma RIII cDNA by a number of point mutations and encodes an additional 21 amino acids at its C-terminus. When transiently expressed neutrophil and NK cell Fc gamma RIII were digested with N-glycanase, deglycosylated neutrophil Fc gamma RIII had a more rapid electrophoretic mobility than NK...
Topics
- Alleles
- Amino Acid Sequence
- Antibodies, Monoclonal
- Antigens, Differentiation
- Cloning, Molecular
- DNA
- Epitopes
- Humans
- Immunoglobulin G
- Killer Cells, Natural