Article
Cross-linking of Fc gamma receptor IIa and Fc gamma receptor IIIb induces different proadhesive phenotypes on human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 1997
Kocher M, Siegel M E, Edberg J C, Kimberly R P
Abstract excerpt
Activation of polymorphonuclear leukocytes (PMN) plays an important role in vascular injury associated with systemic vasculitis and in models of autoantibody- and immune complex-mediated disease. The potential role of intravascular activation of PMN, however, is confounded by the observation that...
Topics
- Alleles
- Antibodies, Antineutrophil Cytoplasmic
- CD18 Antigens
- Cell Adhesion
- Cross-Linking Reagents
- Cyclic AMP
- Down-Regulation
- Epitopes
- Humans
- Immunophenotyping
- L-Selectin
- Macrophage-1 Antigen
- Neutrophil Activation
- Neutrophils
- Protein Structure, Tertiary
- Receptors, IgG
- Up-Regulation