Article
Molecular basis for a polymorphism of human Fc gamma receptor II (CD32).
The Journal of experimental medicine - 1 Jul 1990
Warmerdam P A, van de Winkel J G, Gosselin E J, Capel P J
Abstract excerpt
The IgG Fc receptor II on human monocytes is polymorphic in its ability to bind mIgG1, and its isoelectric focusing pattern. To study the molecular basis of this polymorphism, a cDNA library from cell line K562, expressing two different allelic forms (high responder [HR] and low responder [LR]) o...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigens, Differentiation
- Base Sequence
- Cell Line
- Chromosome Deletion
- Cloning, Molecular
- Gene Library
- Humans
- Isoelectric Focusing
- L Cells
- Mice
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- RNA, Messenger