Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products.

doi:10.1016/s0021-9258(19)49591-4

Article

Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products.

1 Aug 1992

Abstract excerpt

Three distinct but closely related classes of receptors that bind the Fc portion of immunoglobulin G (Fc gamma RI, -II, and -III) have been identified in humans. Only Fc gamma RI has high affinity for ligand and has a unique third extracellular domain (EC3). We have characterized three genes for human Fc gamma RI (A, B, and C). Each gene consists of six exons, spans 9.4 kilobase pairs, and localizes to chromosome...

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