Article
Determination of sheep prion gene polymorphisms from paraffin-embedded tissue.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc - 1 Sept 2006
Kunkle Robert A, Miller Janice M, Alt David P, Cutlip Randall C, Cockett Noelle E, Wang Shiquan, Richt Juergen A, Thomsen Bruce V, Hall S Mark
Abstract excerpt
Amino acid polymorphisms of the prion protein (PrP) greatly influence the susceptibility of sheep to scrapie. Selective breeding to increase the prevalence of PrP gene alleles associated with scrapie resistance is a flock management practice that is important for scrapie control programs. Determination of sheep PrP alleles typically has required extraction of DNA from host tissues that are freshly derived or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.