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Article

Frequencies of PrP gene haplotypes in British sheep flocks and the implications for breeding programmes.

Journal of applied microbiology - 1 Jan 2005

Goldmann W, Baylis M, Chihota C, Stevenson E, Hunter N

Abstract excerpt

AIMS: To analyse the frequencies of prion (PrP) gene haplotypes in UK sheep flocks and evaluate their relevance to transmissible spongiform encephalopathies (TSEs) and TSE resistance breeding programmes in sheep. METHODS AND RESULTS: Genomic DNA isolated from sheep blood was PCR amplified for the coding region of the PrP gene and then sequenced. This study has analysed the sequence of PrP between codons 110 and...

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PMID: 15916643
DOI: 10.1111/j.1365-2672.2005.02568.x

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