Article
Report of outbreaks of classical scrapie in Dorper sheep and associated prion protein gene polymorphisms in affected flocks.
Tropical animal health and production - 1 Aug 2015
de Andrade Caroline Pinto, de Oliveira Eduardo Conceição, Leal Juliano Souza, de Almeida Laura Lopes, de Castro Luiza Amaral, da Silva Sergio Ceroni, Driemeier David
Abstract excerpt
Scrapie is an infectious neurodegenerative disease affecting sheep and goats, related with conformational alteration of an isoform of the prion protein that leads to deposition and aggregation in the host's central nervous system. Occurrence of the natural disease can be influenced by host genetic factors, such as a single nucleotide polymorphism of the prion protein gene. This study reports three...
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