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Article

Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains.

The Journal of biological chemistry - 1 Dec 2006

Hakata Yoshiyuki, Landau Nathaniel R

Abstract excerpt

APOBEC3 proteins comprise a multigene family of antiviral cytidine deaminases that are active against human immunodeficiency virus, simian immunodeficiency virus, endogenous retroelements. The Vif protein of lentiviruses binds to specific APOBEC3 proteins, notably A3F and A3G, to induce their degradation by proteasomes. APOBEC3 proteins are of two types, those with a single deaminase domain such as human (h)A3A...

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Identifiers

PMID: 17020885
DOI: 10.1074/jbc.M604980200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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