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Article

The RNA binding protein Zfp36l1 is required for normal vascularisation and post-transcriptionally regulates VEGF expression.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2006

Bell Sarah E, Sanchez Maria Jose, Spasic-Boskovic Olivera, Santalucia Tomas, Gambardella Laure, Burton Graham J, Murphy John J, Norton John D, Clark Andrew R, Turner Martin

Abstract excerpt

The Zfp36l1 gene encodes a zinc finger-containing mRNA binding protein implicated in the posttranscriptional control of gene expression. Mouse embryos homozygous for a targeted mutation in the Zfp36l1 locus died mid-gestation and exhibited extraembryonic and intraembryonic vascular abnormalities and heart defects. In the developing placenta, there was a failure of the extraembryonic mesoderm to invaginate the...

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Share to Gene Expression Regulation, Developmental
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neovascularization, Physiologic

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Source

Identifiers

PMID: 17013884
DOI: 10.1002/dvdy.20949

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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