Article
The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences.
The Journal of biological chemistry - 16 Feb 1996
Shima D T, Kuroki M, Deutsch U, Ng Y S, Adamis A P, D'Amore P A
Abstract excerpt
We describe the genomic organization and functional characterization of the mouse gene encoding vascular endothelial growth factor (VEGF), a polypeptide implicated in embryonic vascular development and postnatal angiogenesis. The coding region for mouse VEGF is interrupted by seven introns and en...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- DNA Primers
- Endothelial Growth Factors
- Exons
- Genetic Variation
- Humans
- Introns
- Lymphokines
- Mice
- Mice, Inbred Strains