Article
Activation of protein kinase C augments T-type Ca2+ channel activity without changing channel surface density.
The Journal of physiology - 1 Dec 2006
Park Jin-Yong, Kang Ho-Won, Moon Hyung-Jo, Huh Sung-Un, Jeong Seong-Woo, Soldatov Nikolai M, Lee Jung-Ha
Abstract excerpt
T-type Ca2+ channels play essential roles in numerous cellular processes. Recently, we reported that phorbol-12-myristate-13-acetate (PMA) potently enhanced the current amplitude of Cav3.2 T-type channels reconstituted in Xenopus oocytes. Here, we have compared PMA modulation of the activities of...
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