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Article

Modulation of 5-HT3 receptor-mediated response and trafficking by activation of protein kinase C.

The Journal of biological chemistry - 5 Sept 2003

Sun Hui, Hu Xian-Qun, Moradel Edgar M, Weight Forrest F, Zhang Li

Abstract excerpt

Modulation of neurotransmitter-gated membrane ion channels by protein kinase C (PKC) has been the subject of a number of studies. However, less is known about PKC modulation of the serotonin type 3 (5-HT3) receptor, a ligand-gated membrane ion channel that can mediate fast synaptic transmission in the central and peripheral nervous system. Here, we show that PKC potentiated 5-HT3 receptor-mediated current in...

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Identifiers

PMID: 12791692
DOI: 10.1074/jbc.M303584200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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