Article
Protein kinase C modulates inactivation of Kv3.3 channels.
The Journal of biological chemistry - 8 Aug 2008
Desai Rooma, Kronengold Jack, Mei Jianfeng, Forman Stuart A, Kaczmarek Leonard K
Abstract excerpt
Modulation of some Kv3 family potassium channels by protein kinase C (PKC) regulates their amplitude and kinetics and adjusts firing patterns of auditory neurons in response to stimulation. Nevertheless, little is known about the modulation of Kv3.3, a channel that is widely expressed throughout the nervous system and is the dominant Kv3 family member in auditory brainstem. We have cloned the cDNA for the Kv3.3...
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