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Article

The DNA-binding domain of CaNdt80p is required to activate CDR1 involved in drug resistance in Candida albicans.

Journal of medical microbiology - 1 Oct 2006

Wang Jang-Shiun, Yang Yun-Liang, Wu Chin-Jung, Ouyang Karen J, Tseng Kuo-Yun, Chen Chia-Geun, Wang Hsin, Lo Hsiu-Jung

Abstract excerpt

CaNdt80p, the Candida albicans homologue of the Saccharomyces cerevisiae transcription factor ScNdt80p, has been identified as a positive regulator of CDR1, which encodes an efflux pump involved in drug resistance in C. albicans. To investigate the involvement of the putative DNA-binding domain of CaNdt80p in drug resistance, chimeras of CaNdt80p and ScNdt80p were constructed. Interestingly, the DNA-binding...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17005790
DOI: 10.1099/jmm.0.46650-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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