Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA sequencing revealed novel actors of the acquisition of drug resistance in Candida albicans

16 Aug 2012

Abstract excerpt

BACKGROUND: Drug susceptible clinical isolates of Candida albicans frequently become highly tolerant to drugs during chemotherapy, with dreadful consequences to patient health. We used RNA sequencing (RNA-seq) to analyze the transcriptomes of a CDR (Candida Drug Resistance) strain and its isogenic drug sensitive counterpart. RESULTS: RNA-seq unveiled differential expression of 228 genes including a) genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Pneumonia and Respiratory Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22897889
DOI: 10.1186/1471-2164-13-396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA sequencing revealed novel actors of the acquisition of drug resistance in Candida albicansPMID 22897889Read ↗

Hyperexpression of CDRs and HWP1 genes negatively impacts on Candida albicans virulence.Semantic proximity Read ↗

The TAC1 Gene in Candida albicans: Structure, Function, and Role in Azole Resistance: A Mini-Review.Semantic proximity Read ↗

Candida albicans: a historical overview of investigations into an important human pathogenSemantic proximity Read ↗

Coordinated regulation of Mdr1- and Cdr1-mediated protection from antifungals by the Mrr1 transcription factor in emerging <i>Candida</i> sppSemantic proximity Read ↗

All about CDR transporters: Past, present, and futureSemantic proximity Read ↗

Comparative genomic and transcriptomic analyses unveil novel features of azole resistance and adaptation to the human host in Candida glabrata.Semantic proximity Read ↗

The ABCs of Candida albicans Multidrug Transporter Cdr1Semantic proximity Read ↗

Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals.Semantic proximity Read ↗

Genome-Wide Expression Profile Analysis Reveals Coordinately Regulated Genes Associated with Stepwise Acquisition of Azole Resistance in <i>Candida albicans</i> Clinical IsolatesSemantic proximity Read ↗

TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.Semantic proximity Read ↗

Genome-Wide Expression and Location Analyses of the Candida albicans Tac1p RegulonSemantic proximity Read ↗

Update on the structure and function of Candida albicans drug efflux protein, Cdr1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.