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Article

CaNdt80 is involved in drug resistance in Candida albicans by regulating CDR1.

Antimicrobial agents and chemotherapy - 1 Dec 2004

Chen Chia-Geun, Yang Yun-Liang, Shih Hsin-I, Su Chia-Li, Lo Hsiu-Jung

Abstract excerpt

Overexpression of CDR1, an efflux pump, is one of the major mechanisms contributing to drug resistance in Candida albicans. CDR1 p-lacZ was constructed and transformed into a Saccharomyces cerevisiae strain so that the lacZ gene could be used as the reporter to monitor the activity of the CDR1 promoter. Overexpression of CaNDT80, the C. albicans homolog of S. cerevisiae NDT80, increases the beta-galactosidase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15561818
DOI: 10.1128/AAC.48.12.4505-4512.2004
PMCID: PMC529242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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