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Article

Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study.

Hypertension (Dallas, Tex. : 1979) - 1 Nov 2006

Rice Gillian I, Jones Amy L, Grant Peter J, Carter Angela M, Turner Anthony J, Hooper Nigel M

Abstract excerpt

The renin-angiotensin system is a key regulator of blood pressure (BP), with inhibitors of angiotensin-converting enzyme (ACE) used clinically to treat hypertension and other cardiovascular conditions. ACE2 is a newly identified member of this system, which converts angiotensin II to angiotensin, and of which the occurrence in plasma has not been investigated. The aim of this study was to determine the...

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Source

Identifiers

PMID: 17000927
DOI: 10.1161/01.HYP.0000244543.91937.79

Genes

ACE
ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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