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Article

Relationship between genetic variants of ACE2 gene and circulating levels of ACE2 and its metabolites.

Journal of clinical pharmacy and therapeutics - 1 Apr 2018

Chen Y Y, Zhang P, Zhou X M, Liu D, Zhong J C, Zhang C J, Jin L J, Yu H M

Abstract excerpt

WHAT IS KNOWN: Angiotensin-converting enzyme 2 (ACE2) plays an important role in the development of essential hypertension (EH). Genetic factors remarkably influence circulating ACE2 level. OBJECTIVE: Because heritability had remarkable effects on circulating ACE2, we designed this study to shed light on whether circulating levels of ACE2, angiotensin-(1-7) and angiotensin-(1-9) were linked to single nucleotide...

Topics

Aged
Alleles
Angiotensin I
Angiotensin-Converting Enzyme 2
Blood Pressure
Essential Hypertension
Female
Gene Frequency
Genotype
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Peptide Fragments

Peptidyl-Dipeptidase A

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 28895159
DOI: 10.1111/jcpt.12625

Genes

ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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