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Article

Confirmation that the renin gene distal enhancer polymorphism REN-5312C/T is associated with increased blood pressure.

Circulation. Cardiovascular genetics - 1 Feb 2010

Vangjeli Ciara, Clarke Niamh, Quinn Ursula, Dicker Patrick, Tighe Orna, Ho Clara, O'Brien Eoin, Stanton Alice V

Abstract excerpt

BACKGROUND: Studies of knockout and transgenic mice have demonstrated key roles for genes encoding components of the renin angiotensin system in blood pressure regulation. However, whether polymorphisms in these genes contribute to the cause of essential hypertension in humans is still a matter o...

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Identifiers

PMID: 20160196
DOI: 10.1161/CIRCGENETICS.109.899930

Genes

REN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20160196-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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