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Article

Associations of Neprilysin and Its Coding Gene Variation With Hypertension in Chinese Adults.

Journal of clinical hypertension (Greenwich, Conn.) - 1 Apr 2026

Hu Junting, Duan Jing, Jing Jiexiang, Zhang Qiu, Yu Xianfeng, Zhang Rongyan, Jia Yuting, Du Mingzhe, Wang Penghao, Zhang Xueyang, Jin Yibing, Yang Xiangdong, Zhang Mingzhi, Peng Hao, Shen Yun

Abstract excerpt

Neprilysin (NEP) degrades several vasoactive peptides and may contribute to blood pressure maintenance. This study aims to examine the associations between serum NEP levels and variants at its coding gene and hypertension in a general Chinese population. Leveraging the baseline blood specimens of the Gusu cohort, serum NEP was assayed, and 14 single-nucleotide polymorphisms (SNPs) in the MME gene were genotyped...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42001243
DOI: 10.1111/jch.70260
PMCID: PMC13091957

Genes

MME

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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