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Article

CD4+CD25+ regulatory T cells protect against injury in an innate murine model of chronic kidney disease.

Journal of the American Society of Nephrology : JASN - 1 Oct 2006

Mahajan Deepika, Wang Yiping, Qin Xiahong, Wang Ying, Zheng Guoping, Wang Yuan Min, Alexander Stephen I, Harris David C H

Abstract excerpt

Studies of mechanisms of disease regulation by CD4+CD25+ regulatory T cells (Treg) have been focused on their interaction with effector T cells; however, the possibility that regulation might involve noncognate cells has not been explored in detail. This study investigated the effect of CD4+CD25+ Treg on macrophage proinflammatory properties and phenotype in vitro and found that they modulate macrophages by...

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Source

Identifiers

PMID: 16988067
DOI: 10.1681/ASN.2005080842

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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