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Article

IL-10/TGF-beta-modified macrophages induce regulatory T cells and protect against adriamycin nephrosis.

Journal of the American Society of Nephrology : JASN - 1 Jun 2010

Cao Qi, Wang Yiping, Zheng Dong, Sun Yan, Wang Ya, Lee Vincent W S, Zheng Guoping, Tan Thian Kui, Ince Jon, Alexander Stephen I, Harris David C H

Abstract excerpt

IL-10/TGF-beta-modified macrophages, a subset of activated macrophages, produce anti-inflammatory cytokines, suggesting that they may protect against inflammation-mediated injury. Here, macrophages modified ex vivo by IL-10/TGF-beta (IL-10/TGF-beta Mu2) significantly attenuated renal inflammation...

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Identifiers

PMID: 20299353
DOI: 10.1681/ASN.2009060592
PMCID: PMC2900959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20299353-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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