Article
An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.
Hepatology (Baltimore, Md.) - 1 Nov 2004
Cabrera Roniel, Tu Zhengkun, Xu Yiling, Firpi Roberto J, Rosen Hugo R, Liu Chen, Nelson David R
Abstract excerpt
The CD4(+)CD25(+) regulatory T lymphocytes have been implicated in suppressing T cell immune responses. Our aim was to characterize the frequency, phenotype, function, and specificity of CD4(+)CD25(+) T cells in hepatitis C virus (HCV) infection. Peripheral CD4(+)CD25(+) cells from recovered (n = 15), chronic infected (n = 30), and normal control (n = 15) subjects were analyzed ex vivo for quantitation,...
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