Article
An investigation to assess the potential of CD25highCD4+ T cells to regulate responses to donor alloantigens in clinically stable renal transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Jan 2008
Akl Ahmed, Jones Nicholas D, Rogers Nichola, Bakr Mohamed Adel, Mostafa Amani, El Shehawy El Metwaly, Ghoneim Mohamed A, Wood Kathryn J
Abstract excerpt
Regulatory T cells are enriched within CD25(high)CD4(+) leukocytes, however their role in renal transplant recipients with stable function vs. recipients with biopsy-proven chronic allograft dysfunction remains unclear. We therefore studied the number, phenotype, and function of CD25(high)CD4(+) cells in the peripheral blood of 30 renal transplant recipients of living-related grafts, comprising 15 rejection-free...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.